Gene description for CD82
Gene name CD82 molecule
Gene symbol CD82
Other names/aliases 4F9
C33
GR15
IA4
KAI1
R2
SAR2
ST6
TSPAN27
Species Homo sapiens
 Experiment description of studies that identified CD82 in Glioblastoma cells

1
Experiment ID203
Identified moleculemrna
Extracellular vesicle typeMicrovesicles
MISEVEVs
Identification method Microarray
PubMed ID 19011622   
OrganismHomo sapiens
Experiment descriptionGlioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
AuthorsSkog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO
Journal name Nat Cell Biol
Publication year2008
SampleGlioblastoma cells
Sample nameGlioblastoma cells
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Filtration
Flotation density-
Molecules identified in the studyProtein
miRNA
mRNA
Methods used in the studyRT-PCR
Antibody array
Microarray
EV-TRACK -

2
Experiment ID722
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 25802036   
OrganismHomo sapiens
Experiment descriptionGlioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells.
Authorsde Vrij J, Maas SL, Kwappenberg KM, Schnoor R, Kleijn A, Dekker L, Luider TM, de Witte LD, Litjens M, van Strien ME, Hol EM, Kroonen J, Robe PA, Lamfers ML, Schilham MW, Broekman ML.
Journal name Int J Cancer
Publication year2015
SampleGlioblastoma cells
Sample name U87.MG/EGFRvIII
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150064: EV-METRIC:0%, 0%, 29%

3
Experiment ID723
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 25802036   
OrganismHomo sapiens
Experiment descriptionGlioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells.
Authorsde Vrij J, Maas SL, Kwappenberg KM, Schnoor R, Kleijn A, Dekker L, Luider TM, de Witte LD, Litjens M, van Strien ME, Hol EM, Kroonen J, Robe PA, Lamfers ML, Schilham MW, Broekman ML.
Journal name Int J Cancer
Publication year2015
SampleGlioblastoma cells
Sample nameGS184
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150064: EV-METRIC:0%, 0%, 29%

4
Experiment ID1243
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 25261722   
OrganismHomo sapiens
Experiment descriptionInflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells.
AuthorsKore RA, Abraham EC.
Journal name Biochem Biophys Res Commun.
Publication year2014
SampleGlioblastoma cells
Sample nameU373 cells treated with 10ng/ml of TNF-.
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140183: EV-METRIC:22%

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